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Health Safety
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Carcinogenic Effects of Benzene |
The major issue addressed in this document involves the nature and magnitude of the risk of cancer to humans exposed to low levels of benzene. Occupational studies continue to provide the bulk of evidence of benzenes carcinogenicity. Workers are exposed at much higher levels than is the general public. This document verifies that benzene is a known human carcinogen by all routes of exposure. This finding is supported by evidence from human epidemiologic studies, animal data, and an improvement in understanding of mechanism(s) of action. Human epidemiologic studies of highly exposed occupational cohorts have demonstrated that exposure to benzene can cause acute nonlymphocytic leukemia and other blood disorders, that is, preleukemia and aplastic anemia. Additionally, changes in blood and bone marrow consistent with hematotoxicity are recognized in humans and experimental animals. Currently, there is insufficient evidence to reject a linear dose-response curve for benzene in the low-dose region, i.e., that benzene is, in fact, nonlinear in its effects. Because this knowledge is not available at the present time, the Agencys approach of using a model with low-dose linearity is still recommended. Of the various approaches employing a linear assumption, utilizing the Pliofilm workers cohort, the risk at 1 ppm ranges from 4.7 x 10-3 to 2.5 x 10-2. This reaffirms the benzene interim unit risk estimates derived in EPAs 1985 interim risk assessment. There exists very limited data on children from environmental exposure to benzene.
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Environment Safety
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How Can Asbestos Affect My Health? |
From studies of people who were exposed to asbestos in factories and shipyards, we know that breathing high levels of asbestos fibers can lead to an increased risk of:
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Health Safety
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Medicine and Pregnancy |
You still can use many medicines when you are pregnant or nursing. Use this guide and talk to your doctor, nurse, or pharmacist about keeping you and your baby safe.
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Health Safety
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Buying Drugs Online |
Shopping over the Internet is private and easy. Online drug stores let you shop for medicine from your computer. There can also be problems with shopping online. Make sure you know the facts before you buy.
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Health Safety
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Using Medicines Wisely |
Today we have many medicines to choose from. Medicine can help you, but no drug is totally safe. There are things you can do to lower your chances of having problems, and make sure your medicine works the best it can.
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Health Safety
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The Dangers of Listeria and Pregnancy |
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Pregnant women run a serious risk of becoming ill from the bacteria Listeria which can cause miscarriage, fetal death or illness or death of a newborn. If you are pregnant, consuming raw milk - or foods made from raw milk, such as Mexican-style cheese like Queso Blanco or Queso Fresco - can harm your baby even if you don't feel sick. |
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